Pharmaceutical Nanocrystals By Nanomilling Critical
The values for these critical parameters may vary considerably. Typically, the amount of drug in the milling chamber is rather low, from 2 to 30wt, 9, 17, 18, 25-29 while the numbervolume of the milling pearlsbeads is rather high, 1050 of the weightvolume of the slurry. The size of the nanomilling pearls is constant, between 0.5 and 1.0 mm. 9, 17, 25-27, 29, 30 The milling times and.